Multimodal chromatography
Multimodal chromatography is a type of chromatography that uses a combination of different types of interactions between the stationary phase and the target molecule to achieve high selectivity and purification efficiency.
In multimodal chromatography, the stationary phase contains ligands that can interact with the target molecule through multiple modes, such as hydrophobic, electrostatic, hydrogen bonding, and/or metal-ion chelation. This results in a more specific binding of the target molecule to the stationary phase and allows for the purification of molecules with similar physicochemical properties.
Multimodal chromatography can be used for the purification of various biomolecules, such as proteins, peptides, nucleic acids, and viruses. It can also be applied in downstream processing of biopharmaceuticals, as it can efficiently remove impurities and aggregates from the target molecule.
LT Biotech MMC resins can be supplied in 25 ml, 100 ml, 500 ml, 1L, 5 L, 10 L and 20 L plastic bottles or tins, and can be prepacked into 1 ml, 4.7 ml, and 5 ml columns, suitable for the ÄKTA™ system. The catalogue number consists of eight digits, in the format XXX-ZZZZZ. XXX is the product code and ZZZZZ is the pack size in ml. For example, 610-00025 is a 25-ml bottle of Lepta MMC resin, and 624-10000 is a 10 L tin of Lepta 400. For detailed information on pack types and quantities please contact your local distributor or refer to the product list.