Aether DEAE-650 chromatographic resin is based on polyacrylate; the surface has been hydrophilically modified then bonded with weak basic ion-exchange groups. It has high loading capacity, good chemical stability and strong mechanical strength. With small non-specific adsorption, excellent biocompatibility and column bed stability, it can provide a faster flow rate and is especially suitable for large-scale preparation applications. It significantly improves the production efficiency of downstream purification processes, and can reduce costs thus create better economic benefits. It is widely used in capture, intermediate purification and final polishing of antibodies, proteins, peptides, nucleic acids (oligonucleotides), viruses, insulins and other biomolecules.