Helios 50-HQ is a strong anion-exchange resin based on polymers. Compared with traditional agarose chromatography resin, it can be operated under high pressure and high flow rate. It has low backpressure during use, which is convenient for linear amplification and good stability. At the same time, it has high salt tolerance, high resolution, and high and stable protein binding capacity, which can reduce dilution in the purification process, reduce the operation steps of dialysis and ultrafiltration, and improve the process flexibility. It is convenient for the connection of upstream and downstream purification processes, and is widely used in the separation and purification of monoclonal antibodies, recombinant proteins, vaccines, blood products, viruses, DNA and polypeptide products.