Lepta 700 is a multimodal chromatography resin. Different from traditional chromatographic media, it consists of two different structures: the outer shell is a porous passivation layer, which ensures that macromolecules above 700 kDa will not enter the pores and flow directly through the outer layer; the core is coupled and has hydrophobic adsorption. The spherical core of the positively charged adsorption group can bind host proteins, nucleic acids and other impurities to the greatest possible extent. This chromatographic medium can be used effectively for the separation and purification of various macromolecular organisms, such as viruses and virus-like particles. Compared with traditional single mode chromatography media, Lepta 700 shows better performance:

(1) The unique double-layer structure design can process macromolecules above 700 kDa in flow-through mode, making process optimisation easier and more convenient for linear amplification.

(2) The improved Lepta base frame has stronger rigidity, so it can achieve higher process flow rate and improve process efficiency under lower back pressure.

(2) Compared with traditional gel filtration chromatography, it has a larger loading volume and reduces costs.