Helios 50-Q is a strong anion-exchange chromatography resin with polystyrene-divinylbenzene as the base frame, treated with a hydrophilic layer. The chromatographic resin has been greatly improved on the basis of traditional anion exchangers, which reduces the non-specific adsorption of the resin. It can withstand high pressure and operate at high flow rates, and high resolution makes the product yield higher. Impurities are removed. Robust salt tolerance enhances process flexibility and calibration accuracy, and simplifies workflow. In addition, the high dynamic binding capacity can reduce the packing volume of the column bed, saving buffer consumption and circulation. It is widely used in the separation and purification of monoclonal antibodies, recombinant proteins, vaccines, blood products, viruses, DNA and polypeptide products.